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Cell Signal Transduction Research Antibodies
NPT2b Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight75701DaObserved Band:75KD
Protein NameSodium-dependent phosphate transport protein 2B
Human Gene Id10568
Human Swiss Prot NoO95436
Mouse Swiss Prot NoQ9DBP0
Rat Swiss Prot NoQ9JJ09
SpecificityNPT2b Polyclonal Antibody detects endogenous levels of NPT2b protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSLC34A2; Sodium-dependent phosphate transport protein 2B; Sodium-phosphate transport protein 2B; Na(+)-dependent phosphate cotransporter 2B; NaPi3b; Sodium/phosphate cotransporter 2B; Na(+)/Pi cotransporter 2B; NaPi-2b; Solute carrier family 34 member 2
Functiondisease:Defects in SLC34A2 are a cause of pulmonary alveolar microlithiasis [MIM:265100]. Pulmonary alveolar microlithiasis is a rare disease characterized by the deposition of calcium phosphate microliths throughout the lungs. Most patients are asymptomatic for several years or even for decades and generally, the diagnosis is incidental to clinical investigations unrelated to the disease. Cases with early onset or rapid progression are rare. A 'sandstorm-appearing' chest roentgenogram is a typical diagnostic finding. The onset of this potentially lethal disease varies from the neonatal period to old age and the disease follows a long-term, progressive course, resulting in a slow deterioration of lung functions. Pulmonary alveolar microlithiasis is a recessive monogenic disease with full penetrance.,function:May be involved in actively transporting phosphate into cells via Na(+) cotransp
Subcellular LocationMembrane; Multi-pass membrane protein.
ExpressionHighly expressed in lung. Also detected in pancreas, kidney, small intestine, ovary, testis, prostate and mammary gland. In lung, it is found in alveolar type II cells but not in bronchiolar epithelium.,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from NPT2b . at AA range: 630-710
Gene NameSLC34A2
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundsolute carrier family 34 member 2(SLC34A2) Homo sapiens The protein encoded by this gene is a pH-sensitive sodium-dependent phosphate transporter. Phosphate uptake is increased at lower pH. Defects in this gene are a cause of pulmonary alveolar microlithiasis. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, May 2010],
Conjugated Antibody
This product is also available conjugated. Format: E20-75104-Conjugate. Price: $485 / Size: 100μl.
E20-75104-FITC$485 / 100μlE20-75104-Biotin$485 / 100μlE20-75104-HRP$485 / 100μlE20-75104-AP$485 / 100μlE20-75104-AF350$485 / 100μlE20-75104-AF405M$485 / 100μlE20-75104-AF488$485 / 100μlE20-75104-AF514$485 / 100μlE20-75104-AF532$485 / 100μlE20-75104-AF555$485 / 100μlE20-75104-AF568$485 / 100μlE20-75104-AF405S$485 / 100μlE20-75104-AF405L$485 / 100μlE20-75104-AF546$485 / 100μlE20-75104-AF594$485 / 100μlE20-75104-AF610$485 / 100μlE20-75104-AF635$485 / 100μlE20-75104-AF647$485 / 100μlE20-75104-AF680$485 / 100μlE20-75104-AF700$485 / 100μlE20-75104-AF750$485 / 100μlE20-75104-AF790$485 / 100μlE20-75104-APC$485 / 100μlE20-75104-PE$485 / 100μlE20-75104-Cy3$485 / 100μlE20-75104-Cy5$485 / 100μlE20-75104-Cy5.5$485 / 100μlE20-75104-Cy7$485 / 100μlE20-75104-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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