NCX1 Polyclonal Antibody

Name: NCX1 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75103
Price: 225 USD
Availability: InStock

E20-75103Cite ID: EN0055236Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight108547DaObserved Band:108KD

Protein NameSodium/calcium exchanger 1

Human Gene Id6546

Human Swiss Prot NoP32418

Mouse Gene Id20541

Mouse Swiss Prot NoP70414

Rat Gene Id29715

Rat Swiss Prot NoQ01728

SpecificityNCX1 Polyclonal Antibody detects endogenous levels of NCX1 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameSLC8A1; CNC; NCX1; Sodium/calcium exchanger 1; Na(+)/Ca(2+)-exchange protein 1

Functionalternative products:Additional isoforms seem to exist,enzyme regulation:By ATP.,function:Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores.,similarity:Belongs to the sodium/potassium/calcium exchanger family. SLC8 subfamily.,similarity:Contains 2 Calx-beta domains.,tissue specificity:Cardiac sarcolemma.,

Subcellular LocationCell membrane ; Multi-pass membrane protein .

ExpressionDetected primarily in heart and at lower levels in brain (PubMed:1374913). Expressed in cardiac sarcolemma, brain, kidney, liver, pancreas, skeletal muscle, placenta and lung (PubMed:1476165).,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenSynthesized peptide derived from NCX1 . at AA range: 270-350

Gene NameSLC8A1

DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Backgroundsolute carrier family 8 member A1(SLC8A1) Homo sapiens In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.[supplied by OMIM, Apr 2004],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75103-Conjugate. Price: $485 / Size: 100μl.

E20-75103-FITC$485 / 100μlE20-75103-Biotin$485 / 100μlE20-75103-HRP$485 / 100μlE20-75103-AP$485 / 100μlE20-75103-AF350$485 / 100μlE20-75103-AF405M$485 / 100μlE20-75103-AF488$485 / 100μlE20-75103-AF514$485 / 100μlE20-75103-AF532$485 / 100μlE20-75103-AF555$485 / 100μlE20-75103-AF568$485 / 100μlE20-75103-AF405S$485 / 100μlE20-75103-AF405L$485 / 100μlE20-75103-AF546$485 / 100μlE20-75103-AF594$485 / 100μlE20-75103-AF610$485 / 100μlE20-75103-AF635$485 / 100μlE20-75103-AF647$485 / 100μlE20-75103-AF680$485 / 100μlE20-75103-AF700$485 / 100μlE20-75103-AF750$485 / 100μlE20-75103-AF790$485 / 100μlE20-75103-APC$485 / 100μlE20-75103-PE$485 / 100μlE20-75103-Cy3$485 / 100μlE20-75103-Cy5$485 / 100μlE20-75103-Cy5.5$485 / 100μlE20-75103-Cy7$485 / 100μlE20-75103-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.