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Cell Signal Transduction Research Antibodies
RASSF8 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight48327Da
Protein NameRas association domain-containing protein 8
Human Gene Id11228
Human Swiss Prot NoQ8NHQ8
Mouse Swiss Prot NoQ8CJ96
SpecificityRASSF8 Polyclonal Antibody detects endogenous levels of RASSF8 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameRASSF8; C12orf2; Ras association domain-containing protein 8; Carcinoma-associated protein HOJ-1
Observed Band(KD)48
Functiondisease:A chromosomal aberration involving RASSF8 is found in a complex type of synpolydactyly, also referred to as 3/3-prime/4 synpolydactyly associated with metacarpal and metatarsal synostoses [MIM:608180]. Reciprocal translocation t(12;22)(p11.2;q13.3) with FBLN1.,similarity:Contains 1 Ras-associating domain.,tissue specificity:Widely expressed as a 6.2 kb transcript. A 2.2 kb alternatively spliced transcript is expressed exclusively in testis.,
ExpressionLung,Testis,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from RASSF8 . at AA range: 60-140
Gene NameRASSF8
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
BackgroundRas association domain family member 8(RASSF8) Homo sapiens This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011],
Conjugated Antibody
This product is also available conjugated. Format: E20-75100-Conjugate. Price: $485 / Size: 100μl.
E20-75100-FITC$485 / 100μlE20-75100-Biotin$485 / 100μlE20-75100-HRP$485 / 100μlE20-75100-AP$485 / 100μlE20-75100-AF350$485 / 100μlE20-75100-AF405M$485 / 100μlE20-75100-AF488$485 / 100μlE20-75100-AF514$485 / 100μlE20-75100-AF532$485 / 100μlE20-75100-AF555$485 / 100μlE20-75100-AF568$485 / 100μlE20-75100-AF405S$485 / 100μlE20-75100-AF405L$485 / 100μlE20-75100-AF546$485 / 100μlE20-75100-AF594$485 / 100μlE20-75100-AF610$485 / 100μlE20-75100-AF635$485 / 100μlE20-75100-AF647$485 / 100μlE20-75100-AF680$485 / 100μlE20-75100-AF700$485 / 100μlE20-75100-AF750$485 / 100μlE20-75100-AF790$485 / 100μlE20-75100-APC$485 / 100μlE20-75100-PE$485 / 100μlE20-75100-Cy3$485 / 100μlE20-75100-Cy5$485 / 100μlE20-75100-Cy5.5$485 / 100μlE20-75100-Cy7$485 / 100μlE20-75100-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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