Product Information
Molecular Weight115899Da
Protein NamePotassium-transporting ATPase alpha chain 2
Human Gene Id479
Human Swiss Prot NoP54707
Mouse Swiss Prot NoQ9Z1W8
Rat Swiss Prot NoP54708
SpecificityATP1AL1 Polyclonal Antibody detects endogenous levels of ATP1AL1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameATP12A; ATP1AL1; Potassium-transporting ATPase alpha chain 2; Non-gastric H(+)/K(+) ATPase subunit alpha; Proton pump
Observed Band(KD)115
Functioncatalytic activity:ATP + H(2)O + H(+)(In) + K(+)(Out) = ADP + phosphate + H(+)(Out) + K(+)(In).,function:Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues.,similarity:Belongs to the cation transport ATPase (P-type) family. Type IIC subfamily.,subunit:Composed of two subunits: alpha (catalytic) and beta.,tissue specificity:Found in skin and kidney.,
Subcellular Locationplasma membrane,hydrogen:potassium-exchanging ATPase complex,integral component of membrane,basolateral plasma membrane,intracellular membrane-bounded organelle,
ExpressionBrain,Kidney,Skin,Trachea,
BackgroundATPase H+/K+ transporting non-gastric alpha2 subunit(ATP12A) Homo sapiens The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This gene encodes a catalytic subunit of the ouabain-sensitive H+/K+ -ATPase that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for potassium absorption in various tissues. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010],