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Cell Signal Transduction Research Antibodies
IL-12A p35 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight24874Da
Protein NameInterleukin-12 subunit alpha
Human Gene Id3592
Human Swiss Prot NoP29459
Mouse Swiss Prot NoP43431
SpecificityIL-12A p35 Polyclonal Antibody detects endogenous levels of IL-12A p35 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameIL12A; NKSF1; Interleukin-12 subunit alpha; IL-12A; Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; NK cell stimulatory factor chain 1; NKSF1
Observed Band(KD)24
Functionfunction:Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.,online information:Interleukin-12 entry,similarity:Belongs to the IL-6 superfamily.,subunit:Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.,
Subcellular Locationextracellular region,extracellular space,cytoplasm,interleukin-12 complex,
ExpressionBrain,Placenta,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from the Internal region of human IL-12A p35.
Gene NameIL12A
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/50000. Not yet tested in other applications.
Backgroundinterleukin 12A(IL12A) Homo sapiens This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75090-Conjugate. Price: $485 / Size: 100μl.
E20-75090-FITC$485 / 100μlE20-75090-Biotin$485 / 100μlE20-75090-HRP$485 / 100μlE20-75090-AP$485 / 100μlE20-75090-AF350$485 / 100μlE20-75090-AF405M$485 / 100μlE20-75090-AF488$485 / 100μlE20-75090-AF514$485 / 100μlE20-75090-AF532$485 / 100μlE20-75090-AF555$485 / 100μlE20-75090-AF568$485 / 100μlE20-75090-AF405S$485 / 100μlE20-75090-AF405L$485 / 100μlE20-75090-AF546$485 / 100μlE20-75090-AF594$485 / 100μlE20-75090-AF610$485 / 100μlE20-75090-AF635$485 / 100μlE20-75090-AF647$485 / 100μlE20-75090-AF680$485 / 100μlE20-75090-AF700$485 / 100μlE20-75090-AF750$485 / 100μlE20-75090-AF790$485 / 100μlE20-75090-APC$485 / 100μlE20-75090-PE$485 / 100μlE20-75090-Cy3$485 / 100μlE20-75090-Cy5$485 / 100μlE20-75090-Cy5.5$485 / 100μlE20-75090-Cy7$485 / 100μlE20-75090-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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