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Cell Signal Transduction Research Antibodies
IL-28Rα Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight57653Da
Protein NameInterleukin-28 receptor subunit alpha
Human Gene Id163702
Human Swiss Prot NoQ8IU57
Mouse Swiss Prot NoQ8CGK5
SpecificityIL-28Rα Polyclonal Antibody detects endogenous levels of IL-28Rα protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameIL28RA; IFNLR1; LICR2; Interleukin-28 receptor subunit alpha; IL-28 receptor subunit alpha; IL-28R-alpha; IL-28RA; Cytokine receptor class-II member 12; Cytokine receptor family 2 member 12;CRF2-12; Interferon lambda receptor 1; IFN-lambda receptor 1; IFN-lambda-R1; Likely interleukin or cytokine receptor 2; LICR2
Observed Band(KD)57
Functionfunction:The IL28RA/IL10RB dimer is a receptor for IL28A, IL28B and IL29. The ligand/receptor complex seems to signal through the Jak-STAT pathway.,similarity:Belongs to the type II cytokine receptor family.,similarity:Contains 1 fibronectin type-III domain.,subunit:Heterodimer with IL10RB.,tissue specificity:Widely expressed.,
Subcellular Locationplasma membrane,integral component of membrane,interleukin-28 receptor complex,
ExpressionPCR rescued clones,Pooled,Spleen,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from the Internal region of human IL-28Rα.
Gene NameIL28RA
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Backgroundinterferon lambda receptor 1(IFNLR1) Homo sapiens The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75089-Conjugate. Price: $485 / Size: 100μl.
E20-75089-FITC$485 / 100μlE20-75089-Biotin$485 / 100μlE20-75089-HRP$485 / 100μlE20-75089-AP$485 / 100μlE20-75089-AF350$485 / 100μlE20-75089-AF405M$485 / 100μlE20-75089-AF488$485 / 100μlE20-75089-AF514$485 / 100μlE20-75089-AF532$485 / 100μlE20-75089-AF555$485 / 100μlE20-75089-AF568$485 / 100μlE20-75089-AF405S$485 / 100μlE20-75089-AF405L$485 / 100μlE20-75089-AF546$485 / 100μlE20-75089-AF594$485 / 100μlE20-75089-AF610$485 / 100μlE20-75089-AF635$485 / 100μlE20-75089-AF647$485 / 100μlE20-75089-AF680$485 / 100μlE20-75089-AF700$485 / 100μlE20-75089-AF750$485 / 100μlE20-75089-AF790$485 / 100μlE20-75089-APC$485 / 100μlE20-75089-PE$485 / 100μlE20-75089-Cy3$485 / 100μlE20-75089-Cy5$485 / 100μlE20-75089-Cy5.5$485 / 100μlE20-75089-Cy7$485 / 100μlE20-75089-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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