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Cell Signal Transduction Research Antibodies
TudorSN Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight101997Da
Protein NameStaphylococcal nuclease domain-containing protein 1
Human Gene Id27044
Human Swiss Prot NoQ7KZF4
Mouse Gene Id56463
Mouse Swiss Prot NoQ78PY7
Rat Gene Id64635
Rat Swiss Prot NoQ66X93
SpecificityTudorSN Polyclonal Antibody detects endogenous levels of TudorSN protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSND1; TDRD11; Staphylococcal nuclease domain-containing protein 1; 100 kDa coactivator; EBNA2 coactivator p100; Tudor domain-containing protein 11; p100 co-activator
Observed Band(KD)101
Functionfunction:Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).,PTM:Phosphorylated by PIM1 in vitro.,sequence caution:The frameshift leads to wrong initation.,similarity:Contains 1 Tudor domain.,similarity:Contains 4 TNase-like domains.,subcellular location:In IL-4 stimulated cells colocalizes with STAT6 in the nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Binds to acidic transactivation domain of EBNA2. Interacts with EAV NSP1. Interacts with GTF2E1 and GTF2E2. Forms a ternary complex with STAT6 and POLR2A. Interacts with STAT5.,tissue specificity:Ubiquitously expressed.,
Subcellular LocationCytoplasm . Nucleus . Melanosome . In IL-4 stimulated cells colocalizes with STAT6 in the nucleus (PubMed:12234934). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). .
ExpressionUbiquitously expressed.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from the Internal region of human TudorSN.
Gene NameSND1
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/40000. Not yet tested in other applications.
Backgroundstaphylococcal nuclease and tudor domain containing 1(SND1) Homo sapiens This gene encodes a transcriptional co-activator that interacts with the acidic domain of Epstein-Barr virus nuclear antigen 2 (EBNA 2), a transcriptional activator that is required for B-lymphocyte transformation. Other transcription factors that interact with this protein are signal transducers and activators of transcription, STATs. This protein is also thought to be essential for normal cell growth. A similar protein in mammals and other organisms is a component of the RNA-induced silencing complex (RISC). [provided by RefSeq, Jul 2016],
Conjugated Antibody
This product is also available conjugated. Format: E20-75084-Conjugate. Price: $485 / Size: 100μl.
E20-75084-FITC$485 / 100μlE20-75084-Biotin$485 / 100μlE20-75084-HRP$485 / 100μlE20-75084-AP$485 / 100μlE20-75084-AF350$485 / 100μlE20-75084-AF405M$485 / 100μlE20-75084-AF488$485 / 100μlE20-75084-AF514$485 / 100μlE20-75084-AF532$485 / 100μlE20-75084-AF555$485 / 100μlE20-75084-AF568$485 / 100μlE20-75084-AF405S$485 / 100μlE20-75084-AF405L$485 / 100μlE20-75084-AF546$485 / 100μlE20-75084-AF594$485 / 100μlE20-75084-AF610$485 / 100μlE20-75084-AF635$485 / 100μlE20-75084-AF647$485 / 100μlE20-75084-AF680$485 / 100μlE20-75084-AF700$485 / 100μlE20-75084-AF750$485 / 100μlE20-75084-AF790$485 / 100μlE20-75084-APC$485 / 100μlE20-75084-PE$485 / 100μlE20-75084-Cy3$485 / 100μlE20-75084-Cy5$485 / 100μlE20-75084-Cy5.5$485 / 100μlE20-75084-Cy7$485 / 100μlE20-75084-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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