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Cell Signal Transduction Research Antibodies
Stathmin-2 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight20828Da
Protein NameStathmin-2
Human Gene Id11075
Human Swiss Prot NoQ93045
Mouse Gene Id20257
Mouse Swiss Prot NoP55821
Rat Gene Id84510
Rat Swiss Prot NoP21818
SpecificityStathmin-2 Polyclonal Antibody detects endogenous levels of Stathmin-2 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSTMN2; SCG10; SCGN10; Stathmin-2; Superior cervical ganglion-10 protein; Protein SCG10
Observed Band(KD)20
Functionfunction:May play a role in neuronal differentiation, and in modulating membrane interaction with the cytoskeleton during neurite outgrowth.,PTM:Sumoylated.,similarity:Belongs to the stathmin family.,subcellular location:Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. SCG10 exists in both soluble and membrane-bound forms.,tissue specificity:Neuron specific.,
Subcellular LocationCytoplasm . Cytoplasm, perinuclear region . Cell projection, growth cone. Membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, axon. Golgi apparatus. Endosome . Cell projection, lamellipodium. Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. SCG10 exists in both soluble and membrane-bound forms. Colocalized with CIB1 in neurites of developing hippocampal primary neurons (By similarity). Colocalized with CIB1 in the cell body, neuritis and growth cones of neurons. Colocalized with CIB1 to the leading edge of lamellipodia. .
ExpressionNeuron specific.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from the Internal region of human Stathmin-2.
Gene NameSTMN2
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/5000. Not yet tested in other applications.
Backgroundstathmin 2(STMN2) Homo sapiens This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Nov 2010],
Conjugated Antibody
This product is also available conjugated. Format: E20-75076-Conjugate. Price: $485 / Size: 100μl.
E20-75076-FITC$485 / 100μlE20-75076-Biotin$485 / 100μlE20-75076-HRP$485 / 100μlE20-75076-AP$485 / 100μlE20-75076-AF350$485 / 100μlE20-75076-AF405M$485 / 100μlE20-75076-AF488$485 / 100μlE20-75076-AF514$485 / 100μlE20-75076-AF532$485 / 100μlE20-75076-AF555$485 / 100μlE20-75076-AF568$485 / 100μlE20-75076-AF405S$485 / 100μlE20-75076-AF405L$485 / 100μlE20-75076-AF546$485 / 100μlE20-75076-AF594$485 / 100μlE20-75076-AF610$485 / 100μlE20-75076-AF635$485 / 100μlE20-75076-AF647$485 / 100μlE20-75076-AF680$485 / 100μlE20-75076-AF700$485 / 100μlE20-75076-AF750$485 / 100μlE20-75076-AF790$485 / 100μlE20-75076-APC$485 / 100μlE20-75076-PE$485 / 100μlE20-75076-Cy3$485 / 100μlE20-75076-Cy5$485 / 100μlE20-75076-Cy5.5$485 / 100μlE20-75076-Cy7$485 / 100μlE20-75076-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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