Product Information
Molecular Weight27900Da
Protein NameRas-related protein Rab-26
Human Gene Id25837
Human Swiss Prot NoQ9ULW5
Mouse Gene Id328778
Mouse Swiss Prot NoQ504M8
Rat Gene Id171111
Rat Swiss Prot NoP51156
SpecificityRab 26 Polyclonal Antibody detects endogenous levels of Rab 26 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameRAB26; Ras-related protein Rab-26
Observed Band(KD)27
Functionfunction:Participates in exocrine secretion: regulates the secretion of acinar granules in the parotid gland.,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Predominantly expressed in brain.,
Subcellular LocationGolgi apparatus membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, secretory vesicle membrane ; Lipid-anchor ; Cytoplasmic side . Not localized at the plasma membrane (By similarity). Inhibition of S-geranylgeranyl cysteine formation abolishes membrane location. .
ExpressionPredominantly expressed in brain.
BackgroundRAB26, member RAS oncogene family(RAB26) Homo sapiens Members of the RAB protein family, including RAB26, are important regulators of vesicular fusion and trafficking. The RAB family of small G proteins regulates intercellular vesicle trafficking, including exocytosis, endocytosis, and recycling (summary by Seki et al., 2000 [PubMed 11043516]).[supplied by OMIM, Nov 2010],