Product Information
Molecular Weight59978Da
Protein Name[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2 mitochondrial
Human Gene Id57546
Human Swiss Prot NoQ9P2J9
SpecificityPDP2 Polyclonal Antibody detects endogenous levels of PDP2 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NamePDP2; KIAA1348; [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial; PDP 2; Pyruvate dehydrogenase phosphatase catalytic subunit 2; PDPC 2
Observed Band(KD)59
Functioncatalytic activity:[Pyruvate dehydrogenase (acetyl-transferring)] phosphate + H(2)O = [pyruvate dehydrogenase (acetyl-transferring)] + phosphate.,cofactor:Binds 2 magnesium ions per subunit.,function:Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.,similarity:Belongs to the PP2C family.,subunit:Heterodimer of a catalytic subunit and a FAD protein of unknown function.,
Subcellular LocationMitochondrion matrix .
ExpressionBrain,
Backgroundpyruvate dehyrogenase phosphatase catalytic subunit 2(PDP2) Homo sapiens This gene is a mitochondrial protein that functions as a phosphatase and is involved in the enzymatic resetting of the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2016],