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Cell Signal Transduction Research Antibodies
GABAA Rε Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight57972Da
Protein NameGamma-aminobutyric acid receptor subunit epsilon
Human Gene Id2564
Human Swiss Prot NoP78334
SpecificityGABAA Rε Polyclonal Antibody detects endogenous levels of GABAA Rε protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameGABRE; Gamma-aminobutyric acid receptor subunit epsilon; GABA(A) receptor subunit epsilon
Observed Band(KD)57
Functionfunction:GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.,similarity:Belongs to the ligand-gated ionic channel (TC 1.A.9) family.,subunit:Generally pentameric. Associates with alpha and beta subunits.,tissue specificity:Expressed in many tissues. Highest levels of expression in adult heart and placenta.,
Subcellular LocationCell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
ExpressionExpressed in many tissues. Highest levels of expression in adult heart and placenta.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from the Internal region of human GABAA range: Rε.
Gene NameGABRE
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundgamma-aminobutyric acid type A receptor epsilon subunit(GABRE) Homo sapiens The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants have been identified, but only one is thought to encode a protein. [provided by RefSeq, Oct 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75068-Conjugate. Price: $485 / Size: 100μl.
E20-75068-FITC$485 / 100μlE20-75068-Biotin$485 / 100μlE20-75068-HRP$485 / 100μlE20-75068-AP$485 / 100μlE20-75068-AF350$485 / 100μlE20-75068-AF405M$485 / 100μlE20-75068-AF488$485 / 100μlE20-75068-AF514$485 / 100μlE20-75068-AF532$485 / 100μlE20-75068-AF555$485 / 100μlE20-75068-AF568$485 / 100μlE20-75068-AF405S$485 / 100μlE20-75068-AF405L$485 / 100μlE20-75068-AF546$485 / 100μlE20-75068-AF594$485 / 100μlE20-75068-AF610$485 / 100μlE20-75068-AF635$485 / 100μlE20-75068-AF647$485 / 100μlE20-75068-AF680$485 / 100μlE20-75068-AF700$485 / 100μlE20-75068-AF750$485 / 100μlE20-75068-AF790$485 / 100μlE20-75068-APC$485 / 100μlE20-75068-PE$485 / 100μlE20-75068-Cy3$485 / 100μlE20-75068-Cy5$485 / 100μlE20-75068-Cy5.5$485 / 100μlE20-75068-Cy7$485 / 100μlE20-75068-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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