Product Information
Molecular Weight35110Da
Protein NameProtein lifeguard 2
Human Gene Id23017
Human Swiss Prot NoQ9BWQ8
Mouse Swiss Prot NoQ8K097
SpecificityFAIM2 Polyclonal Antibody detects endogenous levels of FAIM2 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameFAIM2; KIAA0950; LFG; LFG2; NMP35; TMBIM2; Protein lifeguard 2; Fas apoptotic inhibitory molecule 2; Neural membrane protein 35; Transmembrane BAX inhibitor motif-containing protein 2
Observed Band(KD)35
Functionfunction:Protects cells uniquely from Fas-induced apoptosis.,similarity:Belongs to the BI1 family.,subunit:Interacts with TNFRSF6.,tissue specificity:Widely expressed. Expressed at high levels in the brain especially in the hippocampus.,
Subcellular LocationCell membrane ; Multi-pass membrane protein . Membrane raft . Cell junction, synapse, postsynaptic cell membrane .
ExpressionHighly expressed in breast carcinoma tissues. Enhanced expression correlates with the grade of the tumor (grade II/grade III) in primary breast tumors (at protein level). Widely expressed. Expressed at high levels in the brain especially in the hippocampus.
Backgroundfunction:Protects cells uniquely from Fas-induced apoptosis.,similarity:Belongs to the BI1 family.,subunit:Interacts with TNFRSF6.,tissue specificity:Widely expressed. Expressed at high levels in the brain especially in the hippocampus.,