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Cell Signal Transduction Research Antibodies
CaMKIIδ Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight56369Da
Protein NameCalcium/calmodulin-dependent protein kinase type II subunit delta
Human Gene Id817
Human Swiss Prot NoQ13557
Mouse Gene Id108058
Mouse Swiss Prot NoQ6PHZ2
Rat Gene Id24246
Rat Swiss Prot NoP15791
SpecificityCaMKIIδ Polyclonal Antibody detects endogenous levels of CaMKIIδ protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCAMK2D; CAMKD; Calcium/calmodulin-dependent protein kinase type II subunit delta; CaM kinase II subunit delta; CaMK-II subunit delta
Observed Band(KD)56
Functioncatalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Autophosphorylation of CAMK2 plays an important role in the regulation of the kinase activity.,function:CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release.,miscellaneous:Expression of CAMK2D is significantly increased in patients suffering from dilated cardiomyopathy.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.,similarity:Contains 1 protein kinase domain.,subunit:CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits.,tissue specificity:Expressed in cardiac muscle and skeletal mus
Subcellular LocationCell membrane, sarcolemma ; Peripheral membrane protein ; Cytoplasmic side . Sarcoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side .
ExpressionExpressed in cardiac muscle and skeletal muscle. Isoform Delta 3, isoform Delta 2, isoform Delta 8 and isoform Delta 9 are expressed in cardiac muscle. Isoform Delta 11 is expressed in skeletal muscle.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from the Internal region of human CaMKIIδ.
Gene NameCAMK2D
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/40000. Not yet tested in other applications.
Backgroundcalcium/calmodulin dependent protein kinase II delta(CAMK2D) Homo sapiens The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.[provided by RefSeq, Nov 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75063-Conjugate. Price: $485 / Size: 100μl.
E20-75063-FITC$485 / 100μlE20-75063-Biotin$485 / 100μlE20-75063-HRP$485 / 100μlE20-75063-AP$485 / 100μlE20-75063-AF350$485 / 100μlE20-75063-AF405M$485 / 100μlE20-75063-AF488$485 / 100μlE20-75063-AF514$485 / 100μlE20-75063-AF532$485 / 100μlE20-75063-AF555$485 / 100μlE20-75063-AF568$485 / 100μlE20-75063-AF405S$485 / 100μlE20-75063-AF405L$485 / 100μlE20-75063-AF546$485 / 100μlE20-75063-AF594$485 / 100μlE20-75063-AF610$485 / 100μlE20-75063-AF635$485 / 100μlE20-75063-AF647$485 / 100μlE20-75063-AF680$485 / 100μlE20-75063-AF700$485 / 100μlE20-75063-AF750$485 / 100μlE20-75063-AF790$485 / 100μlE20-75063-APC$485 / 100μlE20-75063-PE$485 / 100μlE20-75063-Cy3$485 / 100μlE20-75063-Cy5$485 / 100μlE20-75063-Cy5.5$485 / 100μlE20-75063-Cy7$485 / 100μlE20-75063-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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