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Cell Signal Transduction Research Antibodies
BAGE5 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight51200Da
Protein NameBAG family molecular chaperone regulator 5
Human Gene Id9529
Human Swiss Prot NoQ9UL15
Mouse Gene Id70369
Mouse Swiss Prot NoQ8CI32
Rat Gene Id366734
Rat Swiss Prot NoQ5QJC9
SpecificityBAGE5 Polyclonal Antibody detects endogenous levels of BAGE5 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameBAG5; KIAA0873; BAG family molecular chaperone regulator 5; BAG-5; Bcl-2-associated athanogene 5
Observed Band(KD)51
Functionfunction:Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2.,similarity:Contains 4 BAG domains.,subunit:Binds to the ATPase domain of HSP70/HSC chaperones. Binds PARK2.,
Subcellular Locationnucleus,mitochondrion,cytosol,membrane,inclusion body,perinuclear region of cytoplasm,
ExpressionBrain,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from BAGE5 . at AA range: 30-110
Gene NameBAG5
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
BackgroundBCL2 associated athanogene 5(BAG5) Homo sapiens The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75061-Conjugate. Price: $485 / Size: 100μl.
E20-75061-FITC$485 / 100μlE20-75061-Biotin$485 / 100μlE20-75061-HRP$485 / 100μlE20-75061-AP$485 / 100μlE20-75061-AF350$485 / 100μlE20-75061-AF405M$485 / 100μlE20-75061-AF488$485 / 100μlE20-75061-AF514$485 / 100μlE20-75061-AF532$485 / 100μlE20-75061-AF555$485 / 100μlE20-75061-AF568$485 / 100μlE20-75061-AF405S$485 / 100μlE20-75061-AF405L$485 / 100μlE20-75061-AF546$485 / 100μlE20-75061-AF594$485 / 100μlE20-75061-AF610$485 / 100μlE20-75061-AF635$485 / 100μlE20-75061-AF647$485 / 100μlE20-75061-AF680$485 / 100μlE20-75061-AF700$485 / 100μlE20-75061-AF750$485 / 100μlE20-75061-AF790$485 / 100μlE20-75061-APC$485 / 100μlE20-75061-PE$485 / 100μlE20-75061-Cy3$485 / 100μlE20-75061-Cy5$485 / 100μlE20-75061-Cy5.5$485 / 100μlE20-75061-Cy7$485 / 100μlE20-75061-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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