World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
Brm Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight181279Da
Protein NameProbable global transcription activator SNF2L2
Human Gene Id6595
Human Swiss Prot NoP51531
Mouse Gene Id67155
Mouse Swiss Prot NoQ6DIC0
SpecificityBrm Polyclonal Antibody detects endogenous levels of Brm protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSMARCA2; BAF190B; BRM; SNF2A; SNF2L2; Probable global transcription activator SNF2L2; ATP-dependent helicase SMARCA2; BRG1-associated factor 190B; BAF190B;Protein brahma homolog; hBRM; SNF2-alpha; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2
Observed Band(KD)181
Functionfunction:Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the SNF2/RAD54 helicase family.,similarity:Contains 1 bromo domain.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,similarity:Contains 1 HSA domain.,subunit:Component of the BAF complex, which includes at least actin (ACTB), ARID1A, ARID1B/BAF250, SMARCA2, SMARCA4/BRG1, ACTL6A/BAF53, ACTL6B/BAF53B, SMARCE1/BAF57, SMARCC1/BAF155, SMARCC2/BAF170, SMARCB1/SNF5/INI1, and one or mo
Subcellular LocationNucleus .
ExpressionBra
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human Brm. AA range:1328-1377
Gene NameSMARCA2
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
BackgroundSWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2(SMARCA2) Homo sapiens The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [provided by RefSeq, Jan 2014],
Conjugated Antibody
This product is also available conjugated. Format: E20-75039-Conjugate. Price: $485 / Size: 100μl.
E20-75039-FITC$485 / 100μlE20-75039-Biotin$485 / 100μlE20-75039-HRP$485 / 100μlE20-75039-AP$485 / 100μlE20-75039-AF350$485 / 100μlE20-75039-AF405M$485 / 100μlE20-75039-AF488$485 / 100μlE20-75039-AF514$485 / 100μlE20-75039-AF532$485 / 100μlE20-75039-AF555$485 / 100μlE20-75039-AF568$485 / 100μlE20-75039-AF405S$485 / 100μlE20-75039-AF405L$485 / 100μlE20-75039-AF546$485 / 100μlE20-75039-AF594$485 / 100μlE20-75039-AF610$485 / 100μlE20-75039-AF635$485 / 100μlE20-75039-AF647$485 / 100μlE20-75039-AF680$485 / 100μlE20-75039-AF700$485 / 100μlE20-75039-AF750$485 / 100μlE20-75039-AF790$485 / 100μlE20-75039-APC$485 / 100μlE20-75039-PE$485 / 100μlE20-75039-Cy3$485 / 100μlE20-75039-Cy5$485 / 100μlE20-75039-Cy5.5$485 / 100μlE20-75039-Cy7$485 / 100μlE20-75039-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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