Gl Syn Polyclonal Antibody

Name: Gl Syn Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75035
Price: 225 USD
Availability: InStock

E20-75035Cite ID: EN0055168Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight42064Da

Protein NameGlutamine synthetase

Human Gene Id2752

Human Swiss Prot NoP15104

Mouse Gene Id14645

Mouse Swiss Prot NoP15105

Rat Gene Id24957

Rat Swiss Prot NoP09606

SpecificityGl Syn Polyclonal Antibody detects endogenous levels of Gl Syn protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameGLUL; GLNS; Glutamine synthetase; GS; Glutamate decarboxylase; Glutamate--ammonia ligase

Observed Band(KD)42

Functioncatalytic activity:ATP + L-glutamate + NH(3) = ADP + phosphate + L-glutamine.,disease:Defects in GLUL are the cause of congenital systemic glutamine deficiency (CSGD) [MIM:610015]. CSGD is a rare developmental disorder with severe brain malformation resulting in multi-organ failure and neonatal death. Glutamine is largely absent from affected patients serum, urine and cerebrospinal fluid.,online information:Glutamine synthetase entry,similarity:Belongs to the glutamine synthetase family.,subunit:Homooctamer.,

Subcellular LocationCytoplasm, cytosol . Microsome . Mitochondrion . Cell membrane ; Lipid-anchor . Mainly localizes in the cytosol, with a fraction associated with the cell membrane. .

ExpressionExpressed in endothelial cells.

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human Gl Syn. AA range:295-344

Gene NameGLUL

DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Backgroundglutamate-ammonia ligase(GLUL) Homo sapiens The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75035-Conjugate. Price: $485 / Size: 100μl.

E20-75035-FITC$485 / 100μlE20-75035-Biotin$485 / 100μlE20-75035-HRP$485 / 100μlE20-75035-AP$485 / 100μlE20-75035-AF350$485 / 100μlE20-75035-AF405M$485 / 100μlE20-75035-AF488$485 / 100μlE20-75035-AF514$485 / 100μlE20-75035-AF532$485 / 100μlE20-75035-AF555$485 / 100μlE20-75035-AF568$485 / 100μlE20-75035-AF405S$485 / 100μlE20-75035-AF405L$485 / 100μlE20-75035-AF546$485 / 100μlE20-75035-AF594$485 / 100μlE20-75035-AF610$485 / 100μlE20-75035-AF635$485 / 100μlE20-75035-AF647$485 / 100μlE20-75035-AF680$485 / 100μlE20-75035-AF700$485 / 100μlE20-75035-AF750$485 / 100μlE20-75035-AF790$485 / 100μlE20-75035-APC$485 / 100μlE20-75035-PE$485 / 100μlE20-75035-Cy3$485 / 100μlE20-75035-Cy5$485 / 100μlE20-75035-Cy5.5$485 / 100μlE20-75035-Cy7$485 / 100μlE20-75035-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.