ENaC γ Polyclonal Antibody

Name: ENaC γ Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75032
Price: 225 USD
Availability: InStock

E20-75032Cite ID: EN0055165Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight74270Da

Protein NameAmiloride-sensitive sodium channel subunit gamma

Human Gene Id6340

Human Swiss Prot NoP51170

Mouse Gene Id20278

Mouse Swiss Prot NoQ9WU39

Rat Gene Id24768

Rat Swiss Prot NoP37091

SpecificityENaC γ Polyclonal Antibody detects endogenous levels of ENaC γ protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameSCNN1G; Amiloride-sensitive sodium channel subunit gamma; Epithelial Na(+) channel subunit gamma; ENaCG; Gamma-ENaC; Gamma-NaCH; Nonvoltage-gated sodium channel 1 subunit gamma; SCNEG

Observed Band(KD)80

Functiondisease:Defects in SCNN1G are a cause of Liddle syndrome [MIM:177200]. It is an autosomal dominant disorder characterized by pseudoaldosteronism and hypertension associated with hypokalemic alkalosis. The disease is caused by constitutive activation of the renal epithelial sodium channel.,function:Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.,PTM:Phosphorylated on serine and threonine residues.,PTM:Ubiquitinated; this targets individual subunits for endocytosis and proteasome-mediated degradation.,similarity:Belongs to the amiloride-sensitive sodium channel family.,subcellular location:Apical me

Subcellular LocationApical cell membrane ; Multi-pass membrane protein . Apical membrane of epithelial cells. .

ExpressionExpressed in kidney (at protein level).

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human ENaC gamma. AA range:132-181

Gene NameSCNN1G

DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Backgroundsodium channel epithelial 1 gamma subunit(SCNN1G) Homo sapiens Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the gamma subunit, and mutations in this gene have been associated with Liddle syndrome. [provided by RefSeq, Apr 2009],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75032-Conjugate. Price: $485 / Size: 100μl.

E20-75032-FITC$485 / 100μlE20-75032-Biotin$485 / 100μlE20-75032-HRP$485 / 100μlE20-75032-AP$485 / 100μlE20-75032-AF350$485 / 100μlE20-75032-AF405M$485 / 100μlE20-75032-AF488$485 / 100μlE20-75032-AF514$485 / 100μlE20-75032-AF532$485 / 100μlE20-75032-AF555$485 / 100μlE20-75032-AF568$485 / 100μlE20-75032-AF405S$485 / 100μlE20-75032-AF405L$485 / 100μlE20-75032-AF546$485 / 100μlE20-75032-AF594$485 / 100μlE20-75032-AF610$485 / 100μlE20-75032-AF635$485 / 100μlE20-75032-AF647$485 / 100μlE20-75032-AF680$485 / 100μlE20-75032-AF700$485 / 100μlE20-75032-AF750$485 / 100μlE20-75032-AF790$485 / 100μlE20-75032-APC$485 / 100μlE20-75032-PE$485 / 100μlE20-75032-Cy3$485 / 100μlE20-75032-Cy5$485 / 100μlE20-75032-Cy5.5$485 / 100μlE20-75032-Cy7$485 / 100μlE20-75032-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.