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Cell Signal Transduction Research Antibodies
ENT1 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight50219Da
Protein NameEquilibrative nucleoside transporter 1
Human Gene Id2030
Human Swiss Prot NoQ99808
Mouse Gene Id63959
Mouse Swiss Prot NoQ9JIM1
Rat Gene Id63997
Rat Swiss Prot NoO54698
SpecificityENT1 Polyclonal Antibody detects endogenous levels of ENT1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSLC29A1; ENT1; Equilibrative nucleoside transporter 1; Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter;Equilibrative NBMPR-sensitive nucleoside transporter; Nucleoside transporter, es-type; Solute carrier family 29 member 1
Observed Band(KD)55
Functionfunction:Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs).,PTM:Glycosylated.,similarity:Belongs to the SLC29A transporter family.,tissue specificity:Expressed in heart, brain, mammary gland, erythrocytes and placenta, and also in fetal liver and spleen.,
Subcellular LocationBasolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Predominantly localized in the basolateral membrane in polarized MDCK cells.
ExpressionDetected in erythrocytes (at protein level). Expressed in heart, brain, mammary gland, erythrocytes and placenta, and also in fetal liver and spleen.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human ENT1. AA range:15-64
Gene NameSLC29A1
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundsolute carrier family 29 member 1 (Augustine blood group)(SLC29A1) Homo sapiens This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75031-Conjugate. Price: $485 / Size: 100μl.
E20-75031-FITC$485 / 100μlE20-75031-Biotin$485 / 100μlE20-75031-HRP$485 / 100μlE20-75031-AP$485 / 100μlE20-75031-AF350$485 / 100μlE20-75031-AF405M$485 / 100μlE20-75031-AF488$485 / 100μlE20-75031-AF514$485 / 100μlE20-75031-AF532$485 / 100μlE20-75031-AF555$485 / 100μlE20-75031-AF568$485 / 100μlE20-75031-AF405S$485 / 100μlE20-75031-AF405L$485 / 100μlE20-75031-AF546$485 / 100μlE20-75031-AF594$485 / 100μlE20-75031-AF610$485 / 100μlE20-75031-AF635$485 / 100μlE20-75031-AF647$485 / 100μlE20-75031-AF680$485 / 100μlE20-75031-AF700$485 / 100μlE20-75031-AF750$485 / 100μlE20-75031-AF790$485 / 100μlE20-75031-APC$485 / 100μlE20-75031-PE$485 / 100μlE20-75031-Cy3$485 / 100μlE20-75031-Cy5$485 / 100μlE20-75031-Cy5.5$485 / 100μlE20-75031-Cy7$485 / 100μlE20-75031-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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