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Cell Signal Transduction Research Antibodies
CHD1L Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight101000Da
Protein NameChromodomain-helicase-DNA-binding protein 1-like
Human Gene Id9557
Human Swiss Prot NoQ86WJ1
Mouse Gene Id68058
Mouse Swiss Prot NoQ9CXF7
SpecificityCHD1L Polyclonal Antibody detects endogenous levels of CHD1L protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCHD1L; ALC1; Chromodomain-helicase-DNA-binding protein 1-like; Amplified in liver cancer protein 1
Observed Band(KD)101
Functionfunction:Putative DNA helicase, which may play a role in chromatin-remodeling. In vitro, promotes cell proliferation and inhibits apoptois.,similarity:Belongs to the SNF2/RAD54 helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,similarity:Contains 1 Macro domain.,tissue specificity:Frequently overexpresssed in hepatomacellular carcinomas.,
Subcellular LocationNucleus . Localizes at sites of DNA damage. Probably recruited to DNA damage sites by PARylated PARP1. .
ExpressionFrequently overexpressed in hepatomacellular carcinomas.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human CHD1L. AA range:545-594
Gene NameCHD1L
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundchromodomain helicase DNA binding protein 1 like(CHD1L) Homo sapiens This gene encodes a DNA helicase protein involved in DNA repair. The protein converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Several alternatively spliced transcripts variants have been described for this gene. [provided by RefSeq, Jan 2012],
Conjugated Antibody
This product is also available conjugated. Format: E20-75027-Conjugate. Price: $485 / Size: 100μl.
E20-75027-FITC$485 / 100μlE20-75027-Biotin$485 / 100μlE20-75027-HRP$485 / 100μlE20-75027-AP$485 / 100μlE20-75027-AF350$485 / 100μlE20-75027-AF405M$485 / 100μlE20-75027-AF488$485 / 100μlE20-75027-AF514$485 / 100μlE20-75027-AF532$485 / 100μlE20-75027-AF555$485 / 100μlE20-75027-AF568$485 / 100μlE20-75027-AF405S$485 / 100μlE20-75027-AF405L$485 / 100μlE20-75027-AF546$485 / 100μlE20-75027-AF594$485 / 100μlE20-75027-AF610$485 / 100μlE20-75027-AF635$485 / 100μlE20-75027-AF647$485 / 100μlE20-75027-AF680$485 / 100μlE20-75027-AF700$485 / 100μlE20-75027-AF750$485 / 100μlE20-75027-AF790$485 / 100μlE20-75027-APC$485 / 100μlE20-75027-PE$485 / 100μlE20-75027-Cy3$485 / 100μlE20-75027-Cy5$485 / 100μlE20-75027-Cy5.5$485 / 100μlE20-75027-Cy7$485 / 100μlE20-75027-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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