Product Information
Molecular Weight56564Da
Protein NameBeta-1,3-glucosyltransferase
Human Gene Id145173
Human Swiss Prot NoQ6Y288
Mouse Swiss Prot NoQ8BHT6
Specificityβ-1,3-Gal-TL Polyclonal Antibody detects endogenous levels of β-1,3-Gal-TL protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameB3GALTL; B3GTL; Beta-1; 3-glucosyltransferase; Beta3Glc-T; Beta-3-glycosyltransferase-like
Observed Band(KD)57
Functiondisease:Defects in B3GALTL are the cause of Peters-plus syndrome (PPS) [MIM:261540]. PPS is an autosomal recessive disorder characterized by anterior eye-chamber abnormalities, disproportionate short stature, developmental delay, characteristic craniofacial features, cleft lip and/or palate.,function:O-fucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan.,online information:GlycoGene database,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 31 family.,tissue specificity:Widely expressed, with highest levels in testis and uterus.,
Subcellular LocationEndoplasmic reticulum membrane ; Single-pass type II membrane protein .
ExpressionWidely expressed, with highest levels in testis and uterus.
Backgroundbeta 3-glucosyltransferase(B3GLCT) Homo sapiens The protein encoded by this gene is a beta-1,3-glucosyltransferase that transfers glucose to O-linked fucosylglycans on thrombospondin type-1 repeats (TSRs) of several proteins. The encoded protein is a type II membrane protein. Defects in this gene are a cause of Peters-plus syndrome (PPS).[provided by RefSeq, Mar 2009],