Product Information
Molecular Weight17536Da
Protein NameZinc finger HIT domain-containing protein 1
Human Gene Id10467
Human Swiss Prot NoO43257
Mouse Gene Id70103
Mouse Swiss Prot NoQ8R331
SpecificityZNHIT1 Polyclonal Antibody detects endogenous levels of ZNHIT1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameZNHIT1; CGBP1; ZNFN4A1; Zinc finger HIT domain-containing protein 1; Cyclin-G1-binding protein 1; Zinc finger protein subfamily 4A member 1; p18 Hamlet
Observed Band(KD)18-22
Functionfunction:Seems to play a role in p53-mediated apoptosis induction.,induction:Induced by DNA damage.,PTM:Phosphorylated on Thr by MAPK11 or MAPK14.,PTM:Stres-induced ZNHIT1 is mainly regulated at the level of protein.,similarity:Belongs to the ZNHIT1 family.,similarity:Contains 1 HIT-type zinc finger.,subunit:Interacts with MAPK11 and MAPK14. Component of the chromatin-remodeling SRCAP complex composed of at least SRCAP, DMAP1, RUVBL1, RUVBL2, ACTL6A, YEATS4, ACTR6 and ZNHIT1.,
Subcellular LocationNucleus .
ExpressionExpressed abundantly in liver, but weakly in skeletal muscle, ovary and small intestine.
Backgroundfunction:Seems to play a role in p53-mediated apoptosis induction.,induction:Induced by DNA damage.,PTM:Phosphorylated on Thr by MAPK11 or MAPK14.,PTM:Stres-induced ZNHIT1 is mainly regulated at the level of protein.,similarity:Belongs to the ZNHIT1 family.,similarity:Contains 1 HIT-type zinc finger.,subunit:Interacts with MAPK11 and MAPK14. Component of the chromatin-remodeling SRCAP complex composed of at least SRCAP, DMAP1, RUVBL1, RUVBL2, ACTL6A, YEATS4, ACTR6 and ZNHIT1.,