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Cell Signal Transduction Research Antibodies
ZIS Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight37404Da
Protein NameZinc finger Ran-binding domain-containing protein 2
Human Gene Id9406
Human Swiss Prot NoO95218
Mouse Gene Id53861
Mouse Swiss Prot NoQ9R020
Rat Gene Id58821
Rat Swiss Prot NoO35986
SpecificityZIS Polyclonal Antibody detects endogenous levels of ZIS protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameZRANB2; ZIS; ZNF265; Zinc finger Ran-binding domain-containing protein 2; Zinc finger protein 265; Zinc finger; splicing
Observed Band(KD)34
Functiondomain:The RanBP2-type zinc fingers mediate binding to RNA.,function:Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.,PTM:Isoform 2 is phosphorylated on Ser-310 upon DNA damage, probably by ATM or ATR.,sequence caution:Intron retention.,similarity:Belongs to the ZRANB2 family.,similarity:Contains 2 RanBP2-type zinc fingers.,subunit:Interacts with the C-terminal half of SNRNP70, the Arg/Ser-rich domain of XE7 as well as with U2AF1 and CLK1.,
Subcellular LocationNucleus .
ExpressionBrain,Epithelium,Fetal brain,Fetal kidney,Liver,Skin,Testis,Uterus,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human ZNF265. AA range:106-155
Gene NameZRANB2
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Backgrounddomain:The RanBP2-type zinc fingers mediate binding to RNA.,function:Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.,PTM:Isoform 2 is phosphorylated on Ser-310 upon DNA damage, probably by ATM or ATR.,sequence caution:Intron retention.,similarity:Belongs to the ZRANB2 family.,similarity:Contains 2 RanBP2-type zinc fingers.,subunit:Interacts with the C-terminal half of SNRNP70, the Arg/Ser-rich domain of XE7 as well as with U2AF1 and CLK1.,
Conjugated Antibody
This product is also available conjugated. Format: E20-74952-Conjugate. Price: $485 / Size: 100μl.
E20-74952-FITC$485 / 100μlE20-74952-Biotin$485 / 100μlE20-74952-HRP$485 / 100μlE20-74952-AP$485 / 100μlE20-74952-AF350$485 / 100μlE20-74952-AF405M$485 / 100μlE20-74952-AF488$485 / 100μlE20-74952-AF514$485 / 100μlE20-74952-AF532$485 / 100μlE20-74952-AF555$485 / 100μlE20-74952-AF568$485 / 100μlE20-74952-AF405S$485 / 100μlE20-74952-AF405L$485 / 100μlE20-74952-AF546$485 / 100μlE20-74952-AF594$485 / 100μlE20-74952-AF610$485 / 100μlE20-74952-AF635$485 / 100μlE20-74952-AF647$485 / 100μlE20-74952-AF680$485 / 100μlE20-74952-AF700$485 / 100μlE20-74952-AF750$485 / 100μlE20-74952-AF790$485 / 100μlE20-74952-APC$485 / 100μlE20-74952-PE$485 / 100μlE20-74952-Cy3$485 / 100μlE20-74952-Cy5$485 / 100μlE20-74952-Cy5.5$485 / 100μlE20-74952-Cy7$485 / 100μlE20-74952-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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