Product Information
Molecular Weight(Da):50118Observed Band(KD):50
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human ZIP7. at AA rangle: 100-180.
Specificty Sensitivity
Specificity/SensitivityZIP7 Polyclonal Antibody detects endogenous levels of ZIP7 protein.
Storage/StabilityStability:-20°C/1 yearOther Name: SLC39A7; HKE4; RING5; Zinc transporter SLC39A7; Histidine-rich membrane protein Ke4; Really interesting new gene 5 protein; Solute carrier family 39 member 7
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Backgroundsolute carrier family 39 member 7(SLC39A7) Homo sapiens The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],Function:similarity:Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily.,tissue specificity:Major expression in placenta, lung, kidney and pancreas.,
Cellular localizationnucleoplasm,endoplasmic reticulum,endoplasmic reticulum membrane,Golgi apparatus,membrane,integral component of membrane,Expression:Kidney, Platelet, Skin