World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
XRCC2 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight31956Da
Protein NameDNA repair protein XRCC2
Human Gene Id7516
Human Swiss Prot NoO43543
Mouse Swiss Prot NoQ9CX47
SpecificityXRCC2 Polyclonal Antibody detects endogenous levels of XRCC2 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameXRCC2; DNA repair protein XRCC2; X-ray repair cross-complementing protein 2
Observed Band(KD)32
Functionfunction:Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the recA family. RAD51 subfamily.,subunit:Interacts with RAD51D. Part of a BCDX2 complex consisting of RAD51B, RAD51C, RAD51D and XRCC2. Part of a complex consisting of RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3. In the absence of DNA, XRCC2-RAD51D formed a multimeric ring structure. In the presence of single-stranded DNA, XRCC2-RAD51D formed a filamentous structure.,
Subcellular LocationNucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome .
ExpressionBrain,Cervix carcinoma,Testis,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human XRCC2. AA range:211-260
Gene NameXRCC2
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
BackgroundX-ray repair cross complementing 2(XRCC2) Homo sapiens This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-74918-Conjugate. Price: $485 / Size: 100μl.
E20-74918-FITC$485 / 100μlE20-74918-Biotin$485 / 100μlE20-74918-HRP$485 / 100μlE20-74918-AP$485 / 100μlE20-74918-AF350$485 / 100μlE20-74918-AF405M$485 / 100μlE20-74918-AF488$485 / 100μlE20-74918-AF514$485 / 100μlE20-74918-AF532$485 / 100μlE20-74918-AF555$485 / 100μlE20-74918-AF568$485 / 100μlE20-74918-AF405S$485 / 100μlE20-74918-AF405L$485 / 100μlE20-74918-AF546$485 / 100μlE20-74918-AF594$485 / 100μlE20-74918-AF610$485 / 100μlE20-74918-AF635$485 / 100μlE20-74918-AF647$485 / 100μlE20-74918-AF680$485 / 100μlE20-74918-AF700$485 / 100μlE20-74918-AF750$485 / 100μlE20-74918-AF790$485 / 100μlE20-74918-APC$485 / 100μlE20-74918-PE$485 / 100μlE20-74918-Cy3$485 / 100μlE20-74918-Cy5$485 / 100μlE20-74918-Cy5.5$485 / 100μlE20-74918-Cy7$485 / 100μlE20-74918-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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