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Cell Signal Transduction Research Antibodies
Wnt-1 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight40982Da
Protein NameProto-oncogene Wnt-1
Human Gene Id7471
Human Swiss Prot NoP04628
Mouse Gene Id22408
Mouse Swiss Prot NoP04426
SpecificityWnt-1 Polyclonal Antibody detects endogenous levels of Wnt-1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameWNT1; INT1; Proto-oncogene Wnt-1; Proto-oncogene Int-1 homolog
Observed Band(KD)45
Functionfunction:Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters.,similarity:Belongs to the Wnt family.,subunit:Interacts with PORCN. Interacts with RSPO1, RSPO2 and RSPO3.,
Subcellular LocationSecreted, extracellular space, extracellular matrix . Secreted .
ExpressionTestis,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human WNT1. AA range:301-350
Gene NameWNT1
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
BackgroundWnt family member 1(WNT1) Homo sapiens The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in
Conjugated Antibody
This product is also available conjugated. Format: E20-74907-Conjugate. Price: $485 / Size: 100μl.
E20-74907-FITC$485 / 100μlE20-74907-Biotin$485 / 100μlE20-74907-HRP$485 / 100μlE20-74907-AP$485 / 100μlE20-74907-AF350$485 / 100μlE20-74907-AF405M$485 / 100μlE20-74907-AF488$485 / 100μlE20-74907-AF514$485 / 100μlE20-74907-AF532$485 / 100μlE20-74907-AF555$485 / 100μlE20-74907-AF568$485 / 100μlE20-74907-AF405S$485 / 100μlE20-74907-AF405L$485 / 100μlE20-74907-AF546$485 / 100μlE20-74907-AF594$485 / 100μlE20-74907-AF610$485 / 100μlE20-74907-AF635$485 / 100μlE20-74907-AF647$485 / 100μlE20-74907-AF680$485 / 100μlE20-74907-AF700$485 / 100μlE20-74907-AF750$485 / 100μlE20-74907-AF790$485 / 100μlE20-74907-APC$485 / 100μlE20-74907-PE$485 / 100μlE20-74907-Cy3$485 / 100μlE20-74907-Cy5$485 / 100μlE20-74907-Cy5.5$485 / 100μlE20-74907-Cy7$485 / 100μlE20-74907-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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