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Wee 2 Polyclonal Antibody
Datasheet
Catalog Number:
E20-74904Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human WEE2. AA range:151-200Source:
Polyclonal, RabbitGene Name:
WEE2Dilution:
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
- Western blot analysis of lysates from HUVEC cells, using WEE2 Antibody. The lane on the right is blocked with the synthesized peptide.
Background:
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Phosphorylates and inhibits CDC2. May act as a negative regulator of entry into mitosis (G2 to M transition).,PTM:Phosphorylated .,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed in testis.,Protein Name:
Wee1-like protein kinase 2Human Gene Id:
494551Human Swiss Prot No:
P0C1S8Mouse Swiss Prot No:
Q66JT0Specificity:
Wee 2 Polyclonal Antibody detects endogenous levels of Wee 2 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
WEE2; WEE1B; Wee1-like protein kinase 2; Wee1-like protein kinase 1B; Wee1B kinaseMolecularWeight(Da):
62919Observed Band(KD):
60Function:
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Phosphorylates and inhibits CDC2. May act as a negative regulator of entry into mitosis (G2 to M transition).,PTM:Phosphorylated .,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed in testis.,Subcellular Location:
nucleoplasm,cytoplasm,Expression:
Thymus,
- Western blot analysis of the lysates from K562 cells using WEE2 antibody.
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