Product Information
Molecular Weight125967Da
Protein NameWD repeat and HMG-box DNA-binding protein 1
Human Gene Id11169
Human Swiss Prot NoO75717
Mouse Swiss Prot NoP59328
SpecificityWDHD1 Polyclonal Antibody detects endogenous levels of WDHD1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameWDHD1; AND1; WD repeat and HMG-box DNA-binding protein 1; Acidic nucleoplasmic DNA-binding protein 1; And-1
Observed Band(KD)126
Functioncaution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Binds DNA with high affinity. May also be involved in protein-protein interactions.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 HMG box DNA-binding domain.,similarity:Contains 7 WD repeats.,
Subcellular LocationNucleus, nucleoplasm .
ExpressionEmbryonal rhabdomyosarcoma,Epithelium,Fetal brain,Liver,Ski
BackgroundWD repeat and HMG-box DNA binding protein 1(WDHD1) Homo sapiens The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],