Product Information
Molecular Weight26688 Da
Protein NameVesicle transport through interaction with t-SNAREs homolog 1B
Human Gene Id10490
Human Swiss Prot NoQ9UEU0
Mouse Swiss Prot NoO88384
Rat Swiss Prot NoP58200
Specificityv-SNARE Vti1p Polyclonal Antibody detects endogenous levels of v-SNARE Vti1p protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameVTI1B; VTI1; VTI1L; VTI1L1; VTI2; Vesicle transport through interaction with t-SNAREs homolog 1B; Vesicle transport v-SNARE protein Vti1-like 1; Vti1-rp1
Observed Band(KD)26
Functionfunction:V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.,similarity:Belongs to the VTI1 family.,subunit:Found in a complex with VAMP8 and STX7 in the liver. Forms a SNARE complex with STX7, STX8 and VAMP8 which functions in the homotypic fusion of late endosomes. Part of the SNARE core complex containing STX7, STX8 and VAMP8.,tissue specificity:Expressed in all tissues examined.,
Subcellular Locationcytoplasm,lysosomal membrane,endoplasmic reticulum membrane,Golgi apparatus,cytosol,synaptic vesicle,ER to Golgi transport vesicle membrane,integral component of membrane,SNARE complex,late endosome membrane,
ExpressionFibroblast,Glioblastoma,Hypothalamus,Kidney,
Backgroundfunction:V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.,similarity:Belongs to the VTI1 family.,subunit:Found in a complex with VAMP8 and STX7 in the liver. Forms a SNARE complex with STX7, STX8 and VAMP8 which functions in the homotypic fusion of late endosomes. Part of the SNARE core complex containing STX7, STX8 and VAMP8.,tissue specificity:Expressed in all tissues examined.,