Product Information
Molecular Weight39155DaObserved Band:45KD
Protein NameVacuolar protein sorting-associated protein 26B
Human Gene Id112936
Human Swiss Prot NoQ4G0F5
Mouse Gene Id69091
Mouse Swiss Prot NoQ8C0E2
SpecificityVPS26B Polyclonal Antibody detects endogenous levels of VPS26B protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameVPS26B; Vacuolar protein sorting-associated protein 26B; Vesicle protein sorting 26B
Functionfunction:Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the VPS26 family.,subcellular location:Does not localize to endosomes.,subunit:Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35.,
Subcellular Locationendosome,early endosome,late endosome,cytosol,integral component of membrane,retromer complex,retromer, cargo-selective complex,
ExpressionEye,Lung,Placenta,
Backgroundfunction:Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the VPS26 family.,subcellular location:Does not localize to endosomes.,subunit:Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35.,