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Cell Signal Transduction Research Antibodies
VEGF-D Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight40444Da
Protein NameVascular endothelial growth factor D
Human Gene Id2277
Human Swiss Prot NoO43915
Mouse Gene Id14205
Mouse Swiss Prot NoP97946
Rat Gene Id360457
Rat Swiss Prot NoO35251
SpecificityVEGF-D Polyclonal Antibody detects endogenous levels of VEGF-D protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameFIGF; VEGFD; Vascular endothelial growth factor D; VEGF-D; c-Fos-induced growth factor; FIGF
Observed Band(KD)35
Functionfunction:Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (Flk1) and VEGFR-3 (Flt4) receptors.,PTM:Undergoes a complex proteolytic maturation which generates a variety of processed secreted forms with increased activity toward VEGFR-3 and VEGFR-2. VEGF-D first form an antiparallel homodimer linked by disulfide bonds before secretion. The fully processed VEGF-D is composed mostly of two VEGF homology domains (VHDs) bound by non-covalent interactions.,similarity:Belongs to the PDGF/VEGF growth factor family.,subunit:Homodimer; non-covalent and antipar
Subcellular LocationSecreted.
ExpressionHighly expressed in lung, heart, small intestine and fetal lung, and at lower levels in skeletal muscle, colon, and pancreas.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human VEGF-D. AA range:153-202
Gene NameFIGF
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Backgroundvascular endothelial growth factor D(VEGFD) Homo sapiens The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus. [provided by RefSeq, Feb 2011],
Conjugated Antibody
This product is also available conjugated. Format: E20-74872-Conjugate. Price: $485 / Size: 100μl.
E20-74872-FITC$485 / 100μlE20-74872-Biotin$485 / 100μlE20-74872-HRP$485 / 100μlE20-74872-AP$485 / 100μlE20-74872-AF350$485 / 100μlE20-74872-AF405M$485 / 100μlE20-74872-AF488$485 / 100μlE20-74872-AF514$485 / 100μlE20-74872-AF532$485 / 100μlE20-74872-AF555$485 / 100μlE20-74872-AF568$485 / 100μlE20-74872-AF405S$485 / 100μlE20-74872-AF405L$485 / 100μlE20-74872-AF546$485 / 100μlE20-74872-AF594$485 / 100μlE20-74872-AF610$485 / 100μlE20-74872-AF635$485 / 100μlE20-74872-AF647$485 / 100μlE20-74872-AF680$485 / 100μlE20-74872-AF700$485 / 100μlE20-74872-AF750$485 / 100μlE20-74872-AF790$485 / 100μlE20-74872-APC$485 / 100μlE20-74872-PE$485 / 100μlE20-74872-Cy3$485 / 100μlE20-74872-Cy5$485 / 100μlE20-74872-Cy5.5$485 / 100μlE20-74872-Cy7$485 / 100μlE20-74872-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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