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V-ATPase D Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-74860

  • Amount:

    100ul

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    Synthesized peptide derived from V-ATPase D . at AA range: 70-150

  • Source:

    Polyclonal, Rabbit

  • Gene Name:

    ATP6V1D

  • Dilution:

    Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

  • Western blot analysis of ATP6V1D Antibody. The lane on the right is blocked with the ATP6V1D peptide.

  • Background:

    ATPase H+ transporting V1 subunit D(ATP6V1D) Homo sapiens This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein. [provided by RefSeq, Jul 2008],

  • Protein Name:

    V-type proton ATPase subunit D

  • Human Gene Id:

    51382

  • Human Swiss Prot No:

    Q9Y5K8

  • Mouse Gene Id:

    73834

  • Mouse Swiss Prot No:

    P57746

  • Specificity:

    V-ATPase D Polyclonal Antibody detects endogenous levels of V-ATPase D protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    ATP6V1D; ATP6M; VATD; V-type proton ATPase subunit D; V-ATPase subunit D; V-ATPase 28 kDa accessory protein; Vacuolar proton pump subunit D

  • MolecularWeight(Da):

    28263

  • Observed Band(KD):

    28

  • Function:

    function:Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.,similarity:Belongs to the V-ATPase D subunit family.,subunit:V-ATPase is an heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d).,

  • Subcellular Location:

    lysosomal membrane,centrosome,cytosol,cilium,membrane,proton-transporting V-type ATPase complex,extracellular exosome,

  • Expression:

    Bone marrow,Brain,Heart,Pancreatic adenocarcinoma,Pituitary,Placent

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Catalog Number

  • Amount:100ul
  • Price:225$

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V-ATPase D Polyclonal Antibody | EnoGene Biotech Co. Ltd