Product Information
Molecular Weight87978Da
Protein NameU3 small nucleolar RNA-associated protein 14 homolog A
Human Gene Id10813
Human Swiss Prot NoQ9BVJ6
Mouse Gene Id72554
Mouse Swiss Prot NoQ640M1
SpecificityUTP14A Polyclonal Antibody detects endogenous levels of UTP14A protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameUTP14A; SDCCAG16; U3 small nucleolar RNA-associated protein 14 homolog A; Antigen NY-CO-16; Serologically defined colon cancer antigen 16
Observed Band(KD)85
Functionfunction:May be required for ribosome biogenesis.,miscellaneous:The human genome also contains the UTP14C gene, an autosomal retrotransposed copy of this X-linked gene. Evolution of autosomal retrogenes from X-linked progenitors compensates for X-chromosome silencing during male meiosis.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the UTP14 family.,tissue specificity:Ubiquitously expressed.,
Subcellular LocationNucleus, nucleolus .
ExpressionUbiquitously expressed.
BackgroundUTP14A small subunit processome component(UTP14A) Homo sapiens This gene encodes a member of the uridine triphosphate 14 family. As an essential component of a large ribonucleoprotein complex bound to the U3 small nucleolar RNA, the encoded protein is involved in ribosome biogenesis and 18S rRNA synthesis. An autosomal retrotransposed copy of this X-linked gene exists on chromosome 13. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009],