Product Information
Molecular Weight58503Da
Protein NameUbiquitin carboxyl-terminal hydrolase 30
Human Gene Id84749
Human Swiss Prot NoQ70CQ3
Mouse Gene Id100756
Mouse Swiss Prot NoQ3UN04
SpecificityUSP30 Polyclonal Antibody detects endogenous levels of USP30 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameUSP30; Ubiquitin carboxyl-terminal hydrolase 30; Deubiquitinating enzyme 30; Ubiquitin thioesterase 30; Ubiquitin-specific-processing protease 30; Ub-specific protease 30
Observed Band(KD)60kd,unspecial bands( 65kd,105kd,130kd)in Hela and HCT116 cell.
Functioncatalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:May participate in the maintenance of mitochondrial morphology.,similarity:Belongs to the peptidase C19 family.,tissue specificity:Expressed in skeletal muscle, pancreas, liver and kidney.,
Subcellular LocationMitochondrion outer membrane .
ExpressionExpressed in skeletal muscle, pancreas, liver and kidney.
Backgroundubiquitin specific peptidase 30(USP30) Homo sapiens USP30, a member of the ubiquitin-specific protease family (see USP1, MIM 603478), is a novel mitochondrial deubiquitinating (DUB) enzyme (Nakamura and Hirose, 2008 [PubMed 18287522]).[supplied by OMIM, Dec 2008],