Product Information
Molecular Weight14296Da
Protein NameUrotensin-2
Human Gene Id10911
Human Swiss Prot NoO95399
Mouse Swiss Prot NoQ9QZQ3
SpecificityUrotensin II Polyclonal Antibody detects endogenous levels of Urotensin II protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameUTS2; Urotensin-2; Urotensin II; U-II; UII
Observed Band(KD)14
Functionfunction:Highly potent vasoconstrictor.,similarity:Belongs to the urotensin-2 family.,tissue specificity:Brain specific.,
Subcellular LocationSecreted.
ExpressionBrain specific.
Backgroundurotensin 2(UTS2) Homo sapiens This gene encodes a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide. Transcript variants encoding different preproprotein isoforms have been described for this gene. [provided by RefSeq, Jul 2008],