Product Information
Molecular Weight24402Da
Protein NameSerine/threonine-protein kinase ULK3
Human Gene Id25989
Human Swiss Prot NoQ6PHR2
Mouse Gene Id71742
Mouse Swiss Prot NoQ3U3Q1
SpecificityULK3 Polyclonal Antibody detects endogenous levels of ULK3 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameULK3; Serine/threonine-protein kinase ULK3; Unc-51-like kinase 3
Observed Band(KD)24
Functioncatalytic activity:ATP + a protein = ADP + a phosphoprotein.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.,similarity:Contains 1 protein kinase domain.,
Subcellular LocationCytoplasm . Localizes to pre-autophagosomal structure during cellular senescence.
ExpressionWidely expressed. Highest levels observed in fetal brain. In adult tissues, high levels in brain, liver and kidney, moderate levels in testis and adrenal gland and low levels in heart, lung, stomach, thymus, prostate and placenta. In the brain, highest expression in the hippocampus, high levels also detected in the cerebellum, olfactory bulb and optic nerve. In the central nervous system, lowest levels in the spinal cord.
Backgroundcatalytic activity:ATP + a protein = ADP + a phosphoprotein.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.,similarity:Contains 1 protein kinase domain.,