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TWIK-1 Polyclonal Antibody
Datasheet
Catalog Number:
E20-74786Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human KCNK1. AA range:287-336Source:
Polyclonal, RabbitGene Name:
KCNK1Dilution:
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
- Western blot analysis of lysates from Jurkat cells, using KCNK1 Antibody. The lane on the right is blocked with the synthesized peptide.
Background:
potassium two pore domain channel subfamily K member 1(KCNK1) Homo sapiens This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008],Protein Name:
Potassium channel subfamily K member 1Human Gene Id:
3775Human Swiss Prot No:
O00180Mouse Swiss Prot No:
O08581Rat Gene Id:
59324Rat Swiss Prot No:
Q9Z2T2Specificity:
TWIK-1 Polyclonal Antibody detects endogenous levels of TWIK-1 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
KCNK1; HOHO1; KCNO1; TWIK1; Potassium channel subfamily K member 1; Inward rectifying potassium channel protein TWIK-1; Potassium channel KCNO1MolecularWeight(Da):
38143Observed Band(KD):
38Function:
function:Weakly inward rectifying potassium channel.,miscellaneous:Inhibited by barium, quinine, quinidine and internal acidification. Activated by protein kinase C.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Homodimer .,tissue specificity:Widely expressed with high levels in heart and brain and lower levels in placenta, lung, liver and kidney.,Subcellular Location:
endosome,plasma membrane,integral component of plasma membrane,voltage-gated potassium channel complex,integral component of membrane,cytoplasmic, membrane-bounded vesicle,apical plasma membrane,cell junction,dendrite,Expression:
Brain,Kidney,
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