Product Information
Molecular Weight12074DaObserved Band:12KD
Protein NameTumor suppressor candidate 2
Human Gene Id11334
Human Swiss Prot NoO75896
Mouse Gene Id80385
Mouse Swiss Prot NoQ9WVF8
SpecificityTUSC2 Polyclonal Antibody detects endogenous levels of TUSC2 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameTUSC2; C3orf11; FUS1; LGCC; PDAP2; Tumor suppressor candidate 2; Fusion 1 protein; Fus-1 protein; PDGFA-associated protein 2
Functionfunction:May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.,PTM:Myristoylation is required for tumor suppressor activity.,similarity:Belongs to the TUSC2 family.,tissue specificity:Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta.,
Subcellular Locationmitochondrion,
ExpressionPlacenta,
Backgroundtumor suppressor candidate 2(TUSC2) Homo sapiens This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available. [provided by RefSeq, Jul 2008],