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Cell Signal Transduction Research Antibodies

TRIM3 Polyclonal Antibody

E20-74736Cite ID: EN0054869DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight80836 Da
Protein NameTripartite motif-containing protein 3
Human Gene Id10612
Human Swiss Prot NoO75382
Mouse Gene Id55992
Mouse Swiss Prot NoQ9R1R2
Rat Gene Id83616
Rat Swiss Prot NoO70277
SpecificityTRIM3 Polyclonal Antibody detects endogenous levels of TRIM3 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameTRIM3; BERP; RNF22; RNF97; Tripartite motif-containing protein 3; Brain-expressed RING finger protein; RING finger protein 22; RING finger protein 97
Observed Band(KD)81
Functiondomain:The interaction with myosin V is dependent upon its NHL repeats, which form a beta-propeller (NHL) domain containing six blades.,similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 B box-type zinc finger.,similarity:Contains 1 filamin repeat.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 6 NHL repeats.,subunit:Associates with myosin V and alpha-actinin-4 (ACTN4).,tissue specificity:Expressed in brain, heart, uterus and testis.,
Subcellular Locationintracellular,cytoplasm,early endosome,Golgi apparatus,dendrite,
ExpressionBrain,Cerebellum,Cervix,Epithelium,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human TRIM3. AA range:1-50
Gene NameTRIM3
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Backgroundtripartite motif containing 3(TRIM3) Homo sapiens The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified. [provided by RefSeq, Jul 2008],

Conjugated Antibody

This product is also available conjugated. Format: E20-74736-Conjugate. Price: $485 / Size: 100μl.

E20-74736-FITC$485 / 100μlE20-74736-Biotin$485 / 100μlE20-74736-HRP$485 / 100μlE20-74736-AP$485 / 100μlE20-74736-AF350$485 / 100μlE20-74736-AF405M$485 / 100μlE20-74736-AF488$485 / 100μlE20-74736-AF514$485 / 100μlE20-74736-AF532$485 / 100μlE20-74736-AF555$485 / 100μlE20-74736-AF568$485 / 100μlE20-74736-AF405S$485 / 100μlE20-74736-AF405L$485 / 100μlE20-74736-AF546$485 / 100μlE20-74736-AF594$485 / 100μlE20-74736-AF610$485 / 100μlE20-74736-AF635$485 / 100μlE20-74736-AF647$485 / 100μlE20-74736-AF680$485 / 100μlE20-74736-AF700$485 / 100μlE20-74736-AF750$485 / 100μlE20-74736-AF790$485 / 100μlE20-74736-APC$485 / 100μlE20-74736-PE$485 / 100μlE20-74736-Cy3$485 / 100μlE20-74736-Cy5$485 / 100μlE20-74736-Cy5.5$485 / 100μlE20-74736-Cy7$485 / 100μlE20-74736-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.