Product Information
Molecular Weight63955 Da
Protein NameTripartite motif-containing protein 16
Human Gene Id10626
Human Swiss Prot NoO95361
Mouse Swiss Prot NoQ99PP9
SpecificityTRIM16 Polyclonal Antibody detects endogenous levels of TRIM16 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameTRIM16; EBBP; Tripartite motif-containing protein 16; Estrogen-responsive B box protein
Functionfunction:May play a role in the regulation of keratinocyte differentiation.,similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 2 B box-type zinc fingers.,tissue specificity:Highest levels found in testis, ovary, small intestine, colon, placenta, heart, skeletal muscle and mammary gland. More highly expressed in the fetus than in the corresponding adult tissues. Expressed in basal keratinocytes.,
Subcellular Locationintracellular,cytoplasm,PML body,
ExpressionEpithelium,Mammary gland,Placenta,Skin,
Backgroundtripartite motif containing 16(TRIM16) Homo sapiens This gene was identified as an estrogen and anti-estrogen regulated gene in epithelial cells stably expressing estrogen receptor. The protein encoded by this gene contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. The proteins of this family have been reported to be involved in a variety of biological processes including cell growth, differentiation and pathogenesis. Expression of this gene was detected in most tissues. Its function, however, has not yet been determined. [provided by RefSeq, Jul 2008],