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TNNI3K Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-74692

  • Amount:

    100ul

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human TNNI3K. AA range:301-350

  • Source:

    Polyclonal, Rabbit

  • Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using TNNI3K Antibody. The picture on the right is blocked with the synthesized peptide.

  • Gene Name:

    TNNI3K

  • Dilution:

    Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

  • Background:

    TNNI3 interacting kinase(TNNI3K) Homo sapiens This gene encodes a protein that belongs to the MAP kinase kinase kinase (MAPKKK) family of protein kinases. The protein contains ankyrin repeat, protein kinase and serine-rich domains and is thought to play a role in cardiac physiology. [provided by RefSeq, Sep 2012],

  • Protein Name:

    Serine/threonine-protein kinase TNNI3K

  • Human Gene Id:

    51086

  • Human Swiss Prot No:

    Q59H18

  • Mouse Gene Id:

    435766

  • Mouse Swiss Prot No:

    Q5GIG6

  • Rat Gene Id:

    295531

  • Rat Swiss Prot No:

    Q7TQP6

  • Specificity:

    TNNI3K Polyclonal Antibody detects endogenous levels of TNNI3K protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    TNNI3K; CARK; Serine/threonine-protein kinase TNNI3K; Cardiac ankyrin repeat kinase; Cardiac troponin I-interacting kinase; TNNI3-interacting kinase

  • MolecularWeight(Da):

    104179

  • Function:

    catalytic activity:ATP + a protein = ADP + a phosphoprotein.,catalytic activity:GTP + beta-L-fucose 1-phosphate = diphosphate + GDP-L-fucose.,cofactor:Magnesium.,function:Catalyzes the formation of GDP-L-fucose from GTP and L-fucose-1-phosphate. Functions as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids.,function:May play a role in cardiac physiology.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 10 ANK repeats.,subcellular location:Expressed at lower levels in the cytoplasm.,subunit:Interacts with TNNI3, ACTC, ACTA1, MYBPC3, AIP, BABP3 and HADHB.,tissue specificity:Expressed in many tissues.,tissue specificity:Highly expressed in both adult and fetal heart.,

  • Subcellular Location:

    nucleus,cytoplasm,

  • Expression:

    Brain,Colon,Fetal kidney,Heart,Kidney,Stomach mucosa,

  • Western blot analysis of Mouse-kidney lysis using TNNI3K antibody. Antibody was diluted at 1:500. Secondary antibody was diluted at 1:20000

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Catalog Number

  • Amount:100ul
  • Price:225$

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TNNI3K Polyclonal Antibody | EnoGene Biotech Co. Ltd