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TM4SF1 Polyclonal Antibody
Datasheet
Catalog Number:
E20-74675Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human T4S1. AA range:1-50Source:
Polyclonal, RabbitGene Name:
TM4SF1Dilution:
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
- Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using T4S1 Antibody. The picture on the right is blocked with the synthesized peptide.
Background:
transmembrane 4 L six family member 1(TM4SF1) Homo sapiens The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas. [provided by RefSeq, Jul 2008],Protein Name:
Transmembrane 4 L6 family member 1Human Gene Id:
4071Human Swiss Prot No:
P30408Mouse Gene Id:
17112Mouse Swiss Prot No:
Q64302Specificity:
TM4SF1 Polyclonal Antibody detects endogenous levels of TM4SF1 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
TM4SF1; M3S1; TAAL6; Transmembrane 4 L6 family member 1; Membrane component chromosome 3 surface marker 1; Tumor-associated antigen L6MolecularWeight(Da):
21632Function:
similarity:Belongs to the L6 tetraspanin family.,subunit:Present in high molecular weight complexes in tumor cells.,tissue specificity:Highly expressed on lung, breast, colon, and ovarian carcinomas. It is also present on some normal cells, endothelial cells in particular.,Subcellular Location:
integral component of plasma membrane,integral component of membrane,Expression:
Bone marrow,Lung,
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