TFDP1 Polyclonal Antibody

Name: TFDP1 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-74611
Price: 225 USD
Availability: InStock

E20-74611Cite ID: EN0054744Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight45070DaObserved Band:55KD

Protein NameTranscription factor Dp-1

Human Gene Id7027

Human Swiss Prot NoQ14186

Mouse Swiss Prot NoQ08639

SpecificityTFDP1 Polyclonal Antibody detects endogenous levels of TFDP1 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameTFDP1; DP1; Transcription factor Dp-1; DRTF1-polypeptide 1; DRTF1; E2F dimerization partner 1

Functionfunction:Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis.,induction:Down-regulated during differentiation.,miscellaneous:E2F/DP transactivation can be mediated by several cofactors including TBP, TFIIH, MDM2 and CBP.,PTM:Phosphorylation by E2F-1-bound cyclin A-CDK2, in the S phase, inhibits E2F-mediated DNA binding and transactivation.,similarity:Belongs to the E2F/DP family.,subunit:Component of the E2F/DP transcription factor complex. Forms heterodimers with E2F family members. The complex can interact

Subcellular Locationnucleus,nucleoplasm,transcription factor complex,mitochondrion,

ExpressionMuscle,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human DP-1. AA range:361-410

Gene NameTFDP1

DilutionWestern Blot:1/500 - 1/2000. Immunohistochemistry:1/100 - 1/300. Immunofluorescence:1/200 - 1/1000. ELISA:1/20000. Not yet tested in other applications.

Backgroundtranscription factor Dp-1(TFDP1) Homo sapiens This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. The encoded protein functions as part of this complex to control the transcriptional activity of numerous genes involved in cell cycle progression from G1 to S phase. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1, 15, and X.[provided by RefSeq, Jan 2009],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-74611-Conjugate. Price: $485 / Size: 100μl.

E20-74611-FITC$485 / 100μlE20-74611-Biotin$485 / 100μlE20-74611-HRP$485 / 100μlE20-74611-AP$485 / 100μlE20-74611-AF350$485 / 100μlE20-74611-AF405M$485 / 100μlE20-74611-AF488$485 / 100μlE20-74611-AF514$485 / 100μlE20-74611-AF532$485 / 100μlE20-74611-AF555$485 / 100μlE20-74611-AF568$485 / 100μlE20-74611-AF405S$485 / 100μlE20-74611-AF405L$485 / 100μlE20-74611-AF546$485 / 100μlE20-74611-AF594$485 / 100μlE20-74611-AF610$485 / 100μlE20-74611-AF635$485 / 100μlE20-74611-AF647$485 / 100μlE20-74611-AF680$485 / 100μlE20-74611-AF700$485 / 100μlE20-74611-AF750$485 / 100μlE20-74611-AF790$485 / 100μlE20-74611-APC$485 / 100μlE20-74611-PE$485 / 100μlE20-74611-Cy3$485 / 100μlE20-74611-Cy5$485 / 100μlE20-74611-Cy5.5$485 / 100μlE20-74611-Cy7$485 / 100μlE20-74611-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.