Product Information
Molecular Weight26044DaObserved Band:26KD
Protein NameTetraspanin-8
Human Gene Id7103
Human Swiss Prot NoP19075
Mouse Swiss Prot NoQ8R3G9
SpecificityTetraspanin-8 Polyclonal Antibody detects endogenous levels of Tetraspanin-8 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameTSPAN8; TM4SF3; Tetraspanin-8; Tspan-8; Transmembrane 4 superfamily member 3; Tumor-associated antigen CO-029
Functionsimilarity:Belongs to the tetraspanin (TM4SF) family.,tissue specificity:Gastric, colon, rectal, and pancreatic carcinomas.,
Subcellular Locationintegral component of plasma membrane,extracellular exosome,
ExpressionColon carcinoma,Human small intestine,Liver,
Backgroundtetraspanin 8(TSPAN8) Homo sapiens The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008],