Product Information
Molecular Weight59621Da
Protein NameT-complex protein 1 subunit theta
Human Gene Id10694
Human Swiss Prot NoP50990
Mouse Gene Id12469
Mouse Swiss Prot NoP42932
SpecificityTCP-1 θ Polyclonal Antibody detects endogenous levels of TCP-1 θ protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCCT8; C21orf112; CCTQ; KIAA0002; T-complex protein 1 subunit theta; TCP-1-theta; CCT-theta; Renal carcinoma antigen NY-REN-15
Observed Band(KD)60
Functionfunction:Molecular chaperone; assist the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.,similarity:Belongs to the TCP-1 chaperonin family.,subunit:Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. Interacts with PACRG.,
Subcellular Locationzona pellucida receptor complex,nucleoplasm,cytoplasm,centrosome,cytosol,chaperonin-containing T-complex,microtubule,cell-cell adherens junction,cilium,cell body,intermediate filament cytoskeleton,extracellular e
ExpressionAdipose tissue,B-cell lymphoma,Bone marrow,Chondrosarcoma,Epitheliu
Backgroundchaperonin containing TCP1 subunit 8(CCT8) Homo sapiens This gene encodes the theta subunit of the CCT chaperonin, which is abundant in the eukaryotic cytosol and may be involved in the transport and assembly of newly synthesized proteins. Alternative splicing results in multiple transcript variants of this gene. A pseudogene related to this gene is located on chromosome 1. [provided by RefSeq, Sep 2013],