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Cell Signal Transduction Research Antibodies
TCFL5 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight48263Da
Protein NameTranscription factor-like 5 protein
Human Gene Id10732
Human Swiss Prot NoQ9UL49
SpecificityTCFL5 Polyclonal Antibody detects endogenous levels of TCFL5 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameTCFL5; CHA; E2BP1; Transcription factor-like 5 protein; Cha transcription factor; HPV-16 E2-binding protein 1; E2BP-1
Observed Band(KD)48
Functiondevelopmental stage:Isoform 3 is specifically expressed in primary spermatocytes at the pachytene stage, but not those at leptonema stage. Not expressed in other testicular cells, including spermatogonia located in the basal compartment of the seminiferous tubule or spermatids.,disease:Antibodies against TCFL5 are present in sera from patients with Chagas' disease, an autoimmune disease caused by Trypanosoma cruzi. Two different epitopes that mimic Trypanosoma cruzi antigens have been identified: R1 and R3 epitopes, which are recognized by T- and B-cells, respectively.,function:Putative transcription factor. Isoform 3 may play a role in early spermatogenesis.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,tissue specificity:Isoform 3 is testis specific. Isoform 2 is pancreas specific.,
Subcellular Locationmale germ cell nucleus,nucleus,
ExpressionSkin,T lymphoblast,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human TCFL5. AA range:311-360
Gene NameTCFL5
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Backgrounddevelopmental stage:Isoform 3 is specifically expressed in primary spermatocytes at the pachytene stage, but not those at leptonema stage. Not expressed in other testicular cells, including spermatogonia located in the basal compartment of the seminiferous tubule or spermatids.,disease:Antibodies against TCFL5 are present in sera from patients with Chagas' disease, an autoimmune disease caused by Trypanosoma cruzi. Two different epitopes that mimic Trypanosoma cruzi antigens have been identified: R1 and R3 epitopes, which are recognized by T- and B-cells, respectively.,function:Putative transcription factor. Isoform 3 may play a role in early spermatogenesis.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,tissue specificity:Isoform 3 is testis specific. Isoform 2 is pancreas specific.,
Conjugated Antibody
This product is also available conjugated. Format: E20-74582-Conjugate. Price: $485 / Size: 100μl.
E20-74582-FITC$485 / 100μlE20-74582-Biotin$485 / 100μlE20-74582-HRP$485 / 100μlE20-74582-AP$485 / 100μlE20-74582-AF350$485 / 100μlE20-74582-AF405M$485 / 100μlE20-74582-AF488$485 / 100μlE20-74582-AF514$485 / 100μlE20-74582-AF532$485 / 100μlE20-74582-AF555$485 / 100μlE20-74582-AF568$485 / 100μlE20-74582-AF405S$485 / 100μlE20-74582-AF405L$485 / 100μlE20-74582-AF546$485 / 100μlE20-74582-AF594$485 / 100μlE20-74582-AF610$485 / 100μlE20-74582-AF635$485 / 100μlE20-74582-AF647$485 / 100μlE20-74582-AF680$485 / 100μlE20-74582-AF700$485 / 100μlE20-74582-AF750$485 / 100μlE20-74582-AF790$485 / 100μlE20-74582-APC$485 / 100μlE20-74582-PE$485 / 100μlE20-74582-Cy3$485 / 100μlE20-74582-Cy5$485 / 100μlE20-74582-Cy5.5$485 / 100μlE20-74582-Cy7$485 / 100μlE20-74582-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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