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Cell Signal Transduction Research Antibodies
T-cadherin Polyclonal Antibody
Human;Mouse;Rat
WB;IHC-p;IF/ICC;ELISA
Polyclonal, Rabbit,IgG
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight(Da):78287
Protein NameCadherin-13
Human Gene Id1012
Human Swiss Prot NoP55290
Mouse Gene Id12554
Mouse Swiss Prot NoQ9WTR5
SpecificityT-cadherin Polyclonal Antibody detects endogenous levels of T-cadherin protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCDH13; CDHH; Cadherin-13; Heart cadherin; H-cadherin; P105; Truncated cadherin; T-cad; T-cadherin
Observed Band(KD)78
Functiondevelopmental stage:Expressed at higher levels in adult brain than in developing brain.,function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth.,similarity:Contains 5 cadherin domains.,tissue specificity:Highly expressed in heart. In the CNS, expressed in cerebral cortex, medulla, hippocampus, amygdala, thalamus and substantia nigra. No expression detected in cerebellum or spinal cord.,
Subcellular LocationCell membrane; Lipid-anchor, GPI-anchor.
ExpressionHighly expressed in heart. In the CNS, expressed in cerebral cortex, medulla, hippocampus, amygdala, thalamus and substantia nigra. No expression detected in cerebellum or spinal cord.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human CDH13. AA range:331-380
Gene NameCDH13
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
BackgroundThis gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2011],
Conjugated Antibody
This product is also available conjugated. Format: E20-74572-Conjugate. Price: $485 / Size: 100μl.
E20-74572-FITC$485 / 100μlE20-74572-Biotin$485 / 100μlE20-74572-HRP$485 / 100μlE20-74572-AP$485 / 100μlE20-74572-AF350$485 / 100μlE20-74572-AF405M$485 / 100μlE20-74572-AF488$485 / 100μlE20-74572-AF514$485 / 100μlE20-74572-AF532$485 / 100μlE20-74572-AF555$485 / 100μlE20-74572-AF568$485 / 100μlE20-74572-AF405S$485 / 100μlE20-74572-AF405L$485 / 100μlE20-74572-AF546$485 / 100μlE20-74572-AF594$485 / 100μlE20-74572-AF610$485 / 100μlE20-74572-AF635$485 / 100μlE20-74572-AF647$485 / 100μlE20-74572-AF680$485 / 100μlE20-74572-AF700$485 / 100μlE20-74572-AF750$485 / 100μlE20-74572-AF790$485 / 100μlE20-74572-APC$485 / 100μlE20-74572-PE$485 / 100μlE20-74572-Cy3$485 / 100μlE20-74572-Cy5$485 / 100μlE20-74572-Cy5.5$485 / 100μlE20-74572-Cy7$485 / 100μlE20-74572-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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