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TBX22 Polyclonal Antibody
Datasheet
Catalog Number:
E20-74570Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human TBX22. AA range:1-50Source:
Polyclonal, RabbitGene Name:
TBX22Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
- Western blot analysis of lysates from Jurkat and HUVEC cells, using TBX22 Antibody. The lane on the right is blocked with the synthesized peptide.
Background:
T-box 22(TBX22) Homo sapiens This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],Protein Name:
T-box transcription factor TBX22Human Gene Id:
50945Human Swiss Prot No:
Q9Y458Mouse Swiss Prot No:
Q8K402Specificity:
TBX22 Polyclonal Antibody detects endogenous levels of TBX22 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
TBX22; TBOX22; T-box transcription factor TBX22; T-box protein 22MolecularWeight(Da):
57910Observed Band(KD):
58Function:
disease:Defects in TBX22 are the cause of X-linked cleft palate with ankyloglossia (CPX) [MIM:303400].,function:Probable transcriptional regulator involved in developmental processes. This is major determinant crucial to palatogenesis.,similarity:Contains 1 T-box DNA-binding domain.,tissue specificity:Seems to be expressed at a low level.,Subcellular Location:
nucleus,Expression:
Skin,Testis,
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