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Cell Signal Transduction Research Antibodies
TBX2/3 Polyclonal Antibody
Polyclonal, Rabbit
Price on request
Quantity
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight79389 Da
Protein NameT-box transcription factor TBX2/3
Human Gene Id6926
Human Swiss Prot NoO15119/Q13207
Mouse Gene Id21386/21385
Rat Gene Id353305
Rat Swiss Prot NoQ7TST9
SpecificityTBX2/3 Polyclonal Antibody detects endogenous levels of TBX2/3 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameTBX3; T-box transcription factor TBX3; T-box protein 3; TBX2; T-box transcription factor TBX2; T-box protein 2
Observed Band(KD)79
Functiondisease:Defects in TBX3 are the cause of ulnar-mammary syndrome (UMS) [MIM:181450]. UMS is characterized by ulnar ray defects, obesity, hypogenitalism, delayed puberty, hypoplasia of nipples and apocrine glands.,function:Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation.,similarity:Contains 1 T-box DNA-binding domain.,tissue specificity:Widely expressed.,
Subcellular LocationNucleus .
ExpressionWidely expressed.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human TBX3. AA range:271-320
Gene NameTBX2/TBX3
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
BackgroundT-box 3(TBX3) Homo sapiens This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-74569-Conjugate. Price: $485 / Size: 100μl.
E20-74569-FITC$485 / 100μlE20-74569-Biotin$485 / 100μlE20-74569-HRP$485 / 100μlE20-74569-AP$485 / 100μlE20-74569-AF350$485 / 100μlE20-74569-AF405M$485 / 100μlE20-74569-AF488$485 / 100μlE20-74569-AF514$485 / 100μlE20-74569-AF532$485 / 100μlE20-74569-AF555$485 / 100μlE20-74569-AF568$485 / 100μlE20-74569-AF405S$485 / 100μlE20-74569-AF405L$485 / 100μlE20-74569-AF546$485 / 100μlE20-74569-AF594$485 / 100μlE20-74569-AF610$485 / 100μlE20-74569-AF635$485 / 100μlE20-74569-AF647$485 / 100μlE20-74569-AF680$485 / 100μlE20-74569-AF700$485 / 100μlE20-74569-AF750$485 / 100μlE20-74569-AF790$485 / 100μlE20-74569-APC$485 / 100μlE20-74569-PE$485 / 100μlE20-74569-Cy3$485 / 100μlE20-74569-Cy5$485 / 100μlE20-74569-Cy5.5$485 / 100μlE20-74569-Cy7$485 / 100μlE20-74569-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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