Product Information
Molecular Weight(Da):74068
Protein NameT-box transcription factor TBX2
Human Gene Id6909
Human Swiss Prot NoQ13207
Mouse Gene Id21385
Mouse Swiss Prot NoQ60707
SpecificityTBX2 Polyclonal Antibody detects endogenous levels of TBX2 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameTBX2; T-box transcription factor TBX2; T-box protein 2
Observed Band(KD)74
Functionfunction:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation.,similarity:Contains 1 T-box DNA-binding domain.,tissue specificity:Expressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary.,
Subcellular LocationNucleus .
ExpressionExpressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary.
BackgroundT-box 2(TBX2) Homo sapiens This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene. [provided by RefSeq, Jul 2008],