Product Information
Molecular Weight62199 DaObserved Band:62 Da
Protein NameTBC1 domain family member 3
Human Gene Id414059/727735/84218/643947/414060/653380/654341/729873
Human Swiss Prot NoQ8IZP1/A6NDS4/Q6IPX1
SpecificityTBC1D3A/B/C Polyclonal Antibody detects endogenous levels of TBC1D3A/B/C protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameTBC1D3; PRC17; TBC1D3A; TBC1 domain family member 3; Prostate cancer gene 17 protein; Protein TRE17-alpha; Rab GTPase-activating protein PRC17; TBC1D3B; TBC1D3I; TBC1 domain family member 3B; TBC1D3C; TBC1D3D; TBC1 domain family member 3C
Functiondisease:May be involved in forms of prostate cancers.,function:Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11.,similarity:Contains 1 Rab-GAP TBC domain.,tissue specificity:Expressed in liver, skeletal muscle, kidney, pancreas, spleen, testis, ovary, small intestine and peripheral blood leukocytes. Overexpressed in prostate cancers.,tissue specificity:Expressed in pancreas, thymus and testis.,
Subcellular LocationCell membrane ; Lipid-anchor . Associated with lipid rafts.
ExpressionExpressed in liver, skeletal muscle, kidney, pancreas, spleen, testis, ovary, small intestine and peripheral blood leukocytes. Overexpressed in prostate cancers.
BackgroundTBC1 domain family member 3C(TBC1D3C) Homo sapiens This gene represents one of a cluster of related genes found on chromosome 17. The proteins encoded by this gene family contain a TBC (Tre-2, Bub2p, and Cdc16p) domain and may be involved in GTPase signaling and vesicle trafficking. [provided by RefSeq, Apr 2014],